History

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  2. History
Year Organization and Research Grant Study Group
1978 Initial research was started, based on the grant "A Study on the Multidisciplinary Treatment of Cancer", funded by a Grant-in-Aid for Cancer Research from the Ministry of Health and Welfare. The Principal Investigator was Keiichi Suemasu, M.D. The Lymphoma Study Group (LSG)
The Japan Esophageal Oncology Group (JEOG)
1982   The Lung Cancer Study Group (LCSG)
1984   The Gastric Cancer Surgical Study Group (GCSSG) (currently the Stomach Cancer Study Group)
1985  

The Gastrointestinal Oncology Study Group (GIOSG)
The Breast Cancer Study Group (BCSG)

 

Clinical Trial Review Committee (now Protocol Review Committee)

Data and Safety Monitoring Committee

1986 Constitution and Bylaws established.The Clinical Trials Review Committee (currently the Protocol Review Committee) and Data and Safety Monitoring Committee were instituted. The Lung Cancer Surgical Study Group (LCSSG)
1987 The Steering Committee Meeting (currently the Executive Committee Meeting) was established.  
1988 A new Grant-in-Aid was received from the Ministry of Health and Welfare , for a project titled "A Study on the Multidisciplinary Treatment of Solid Cancer". The Principal Investigator was Masanori Shimoyama, M.D.  
1990 The organization was named "JCOG (Japan Clinical Oncology Group)".
Dr. Masanori Shimoyama became the first JCOG Chair.
Autologous Bone Marrow Transplant Group
1991 The "JCOG Statistical Center" (now called the JCOG Data Center) was established, and began central patient registration and randomization using the minimization method.  
1995   The Gynecologic Cancer Study Group (GCSG)
1996   Autologous Bone Marrow Transplant Group disbanded and merged into Lymphoma Study Group and Breast Cancer Study Group
1999 "A Study on the Multidisciplinary Treatment of Solid Cancer" was divided into four groups:

  • "Multi-institutional Cooperative Study to Establish the Standard Therapy of Chemosensitive Malignant Tumors (14S-1)";
  • "Study on Establishment of a Global Standard in the Treatment of Lung Cancer (14S-2)"
  • "Studies on Multi-institutional Trials for Establishing Standard Therapy for Gastrointestinal Cancers (14S-3)";
  • "Study on Establishment of a High-quality Clinical Trial System through a Cooperative Group Mechanism (14S-4)".
Quality Assurance Audit Committee, Education and Training Committee, Surgery Committee, and Radiotherapy Committee were established.
JCOG8801 was published at The Lancet
2000  

Audit Comittee

Education and Training Committee

Surgical Committee

Radiotherapy Committee

2001 Dr. Nagahiro Saijo became the second JCOG Chair.
JCOG took part in the national project "Medical Frontier Strategy Research" (superseded since 2002 by "Clinical Research for Evidence Based Medicine") with a Health Sciences Research Grant.

The Colorectal Cancer Study Group (CCSG)
The Urologic Oncology Group (UOSG)

 

Pathology Committee

2002  

The Bone and Soft Tissue Tumor Study Group (BSTTSG)

JCOG9511 was published at New England Journal of Medicine

2003  

The Radiation Therapy Study Group (RTSG)
The Brain Tumor Study Group (BTSG)

 

Clinical Research Professionals Committee

2004 A new competitive grant system from the Ministry of Health, Labour and Welfare was initiated, called "Health and Labour Sciences Research Grant for Clinical Cancer Research".  
2005 JCOG study activity incorporated a new Grant-in-Aid for Cancer Research, titled "Multi-institutional Cooperative Studies for the Establishment of Standard Therapy of Rare Malignant Tumors (17S-4)".

Protocol Review Committee

Translational Research Committee

Regulatory Affairs Committee

2006 The JCOG central office was reorganized into the JCOG Data Center and JCOG Operations Office.
The NPO CORE (Non-Profit Organization Clinical Oncology Research and Education) was established, collaboratively managing the JCOG Data Center / Operations Office with the National Cancer Center.
 
2007   The first investigator initiated registration trial called "JCOG0604" was initiated
2008 A new Grant-in-Aid for Cancer Research, titled "Multi-institutional Cooperative Studies for the Establishment of Standard Therapy of Radiation Therapy (20S-5)" was added to the JCOG study activity.
An international collaborative study with South Korea was begun.

The Hepatobiliary and Pancreatic Oncology Group (HBPOG)

 

JCOG9501 was published at New England Journal of Medicine

 

The first international collaborative trial called "JCOG0705/KGCA01" was initiated

 

Diagnostic Radiology Committee

2009 Dr. Tomohide Tamura became the third JCOG Chair.  
2010   Conflict of Interest Committee
2011 The Grant-in-Aid for Cancer Research was reorganized into the "National Cancer Center Research and Development Fund". JCOG activity was funded by 7 research grants: 23-A-16, 23-A-17, 23-A-18, 23-A-19, 23-A-20, 23-A-21, 23-A-22.

The Gastrointestinal Endoscopy Study Group (GIESG)
The Head and Neck Cancer Study Group (HNCSG)
The Gastric Cancer Surgical Study Group (GCSSG) incorporated a part of the Gastrointestinal Oncology Study Group (GIOSG) and was renamed the Stomach Cancer Study Group (SCSG). The other section of GIOSG was reorganized into GIESG and HNCSG.

 

 

JCOG Biobank was established

2012   The Dermatologic Oncology Group (DOG)
2013   The first clinical trial called "JCOG1111C" was initiated in JCOG under the Advance Medical Care B 
2014 Seven research grants of National Cancer Center Research and Development Fund were integrated into 26-A-4 (Scientific research on multi-institutional trials to establish new standard treatment of solid tumors in adults) chaired by Dr. Kensei Tobinai.  
2014 Dr. Kensei Tobinai became the fourth JCOG Chair. Start of collaboration with Biobank Japan (BBJ) 
2016   Geriatric Study Committee
2017

Dr. Yuichiro Ohe became the fifth JCOG Chair.


National Cancer Center Research and Development was renewed as 29-A-3 (Scientific research on multi-institutional trials to establish new standard treatment of solid tumors in adults: JCOG)

 
2018

 

End of collaboration with Biobank Japan (BBJ) for genome analysis function
2020 National Cancer Center Research and Development was renewed as 2020-J-3 (Scientific research on multi-institutional trials to establish new standard treatment of solid tumors in adults: JCOG)  
2021   PRO/QOL research committee
2022  

Patient and Public Involvement Committee

JCOG0802/WJOG4607L was published at The Lancet

2023 National Cancer Center Research and Development was renewed as 2023-J-03 (Scientific research on multi-institutional trials to establish new standard treatment of solid tumors in adults: JCOG) JCOG1202 was pulished at The Lancet
2024  

International Committee

JCOG1109 was pulished at The Lancet

2025 Dr. Yukihide Kanemitsu became the sixth JCOG Chair.  

The detailed structure and history of JCOG can be found in the following article:

Fukuda H. Development of Cancer Cooperative Groups in Japan. Jpn J Clin Oncol 2010;40(9)881-890.